Hans-Christoph Pape Selected Research

Acute Lung Injury

1/2020	Complement Activation and Organ Damage After Trauma-Differential Immune Response Based on Surgical Treatment Strategy.
6/2015	Development of a standardized trauma-related lung injury model.
4/2012	Do stable multiply injured patients with bilateral femur fractures have higher complication rates? An investigation by the EPOFF study group.
1/2009	IL-10 deficiency augments acute lung but not liver injury in hemorrhagic shock.
12/2008	Local exposure of bone components to injured soft tissue induces Toll-like receptor 4-dependent systemic inflammation with acute lung injury.
9/2007	Impact of the method of initial stabilization for femoral shaft fractures in patients with multiple injuries at risk for complications (borderline patients).

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Hans-Christoph Pape Research Topics

Disease

88	Wounds and Injuries (Trauma) 03/2024 - 03/2002
34	Multiple Trauma (Multiple Injuries) 03/2024 - 06/2002
22	Hemorrhagic Shock 03/2024 - 07/2002
20	Sepsis (Septicemia) 03/2024 - 11/2002
18	Inflammation (Inflammations) 01/2022 - 10/2003
18	Hemorrhage 04/2021 - 07/2002
15	Infections 11/2023 - 03/2004
13	Shock 02/2023 - 11/2002
10	Multiple Organ Failure (MODS) 01/2021 - 11/2004
10	Femoral Fractures (Femoral Fracture) 11/2020 - 10/2002
7	Lacerations 03/2024 - 06/2014
7	Pneumonia (Pneumonitis) 10/2022 - 09/2008
6	Hypothermia 02/2023 - 03/2004
6	Pain (Aches) 01/2023 - 03/2004
6	Disease Progression 03/2021 - 03/2005
6	Contusions 01/2021 - 04/2005
6	Acute Lung Injury 01/2020 - 09/2007
5	Soft Tissue Injuries (Soft Tissue Injury) 02/2022 - 06/2010
5	Open Fractures (Compound Fracture) 02/2022 - 02/2013
4	Humeral Fractures 11/2023 - 01/2015
4	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2021 - 03/2007
4	Edema (Dropsy) 07/2008 - 09/2006
3	Ischemia 03/2024 - 08/2007
3	Periprosthetic Fractures 03/2023 - 06/2011
3	Traumatic Brain Injuries (Traumatic Brain Injury) 02/2023 - 03/2002
3	Rupture 05/2019 - 03/2015
2	Compartment Syndromes 08/2023 - 05/2007
2	Contracture 01/2023 - 01/2017
2	COVID-19 10/2022 - 01/2020
2	Femoral Neck Fractures 01/2022 - 12/2016
2	Compression Fractures (Compression Fracture) 10/2021 - 01/2018
2	Osteomyelitis 03/2021 - 09/2018
2	Myocardial Contusions 01/2020 - 02/2003
2	Lung Injury 12/2017 - 06/2015
2	Congenital Abnormalities (Deformity) 01/2017 - 02/2005
2	Cicatrix (Scar) 01/2017 - 03/2015
2	Surgical Wound Infection 03/2015 - 02/2013
2	Shoulder Fractures 01/2015 - 07/2013
2	Thoracic Injuries (Chest Injury) 06/2010 - 02/2005
2	Hypersensitivity (Allergy) 03/2006 - 11/2002
1	Mitochondrial Diseases (Mitochondrial Disease) 03/2024
1	Spinal Injuries (Spinal Injury) 11/2023

Drug/Important Bio-Agent (IBA)

19	CytokinesIBA 12/2020 - 10/2003
18	Interleukin-6 (Interleukin 6)IBA 11/2020 - 10/2003
13	Interleukin-10 (Interleukin 10)IBA 12/2017 - 07/2002
10	salicylhydroxamic acid (SHAM)IBA 01/2020 - 11/2002
9	Peroxidase (Myeloperoxidase)IBA 05/2014 - 09/2006
6	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2007 - 07/2002
5	Lactic Acid (Lactate)FDA LinkGeneric 03/2024 - 11/2007
5	Anti-Bacterial Agents (Antibiotics)IBA 09/2022 - 06/2010
5	Interleukin-8 (Interleukin 8)IBA 11/2020 - 02/2007
4	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2015
4	Dehydroepiandrosterone (DHEA)IBA 05/2014 - 07/2002
3	Indicators and Reagents (Reagents)IBA 03/2024 - 10/2021
3	ElementsIBA 08/2023 - 04/2011
3	Ringer's LactateIBA 02/2013 - 07/2002
2	C-Reactive ProteinIBA 11/2021 - 01/2015
2	Troponin IIBA 01/2021 - 01/2020
2	Fatty Acid-Binding ProteinsIBA 01/2021 - 01/2021
2	Complement System Proteins (Complement)IBA 12/2020 - 01/2020
2	AcidsIBA 01/2020 - 01/2020
2	SolutionsIBA 05/2019 - 04/2011
2	Interleukin-18 (Interleukin 18)IBA 12/2017 - 09/2011
2	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 06/2013 - 11/2012
2	Toll-Like Receptors (Toll-Like Receptor)IBA 06/2013 - 12/2008
2	InterleukinsIBA 09/2011 - 06/2006
2	Hormones (Hormone)IBA 11/2007 - 07/2002
2	SteroidsIBA 02/2007 - 07/2002
2	Flutamide (Eulexin)FDA LinkGeneric 11/2006 - 10/2006
2	Estrogen ReceptorsIBA 09/2006 - 06/2006
2	4,4',4''- (4- propyl- ((1)H)- pyrazole- 1,3,5- triyl) tris-phenolIBA 09/2006 - 06/2006
2	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 03/2006 - 03/2005
1	acylcarnitineIBA 03/2024

Therapy/Procedure

24	Resuscitation 03/2024 - 07/2002
20	Fracture Fixation 01/2024 - 03/2002
15	Length of Stay 11/2023 - 02/2006
14	Intramedullary Fracture Fixation 01/2023 - 11/2005
10	Therapeutics 03/2023 - 10/2003
7	Critical Care (Surgical Intensive Care) 10/2018 - 02/2005
7	Punctures 08/2009 - 07/2002
6	Arthroplasty 11/2023 - 06/2011
6	Ligation 08/2009 - 11/2002
5	Laparotomy 01/2020 - 06/2006
5	Surgical Amputation (Amputations) 05/2011 - 01/2004
4	Negative-Pressure Wound Therapy 02/2022 - 12/2008
4	Operative Surgical Procedures 06/2019 - 10/2002
4	Orthopedic Procedures 01/2015 - 06/2002
4	Induced Hypothermia 12/2014 - 03/2004
3	Fasciotomy 08/2023 - 05/2007
3	Operative Time 01/2023 - 02/2013
3	Osteotomy 12/2021 - 06/2004
3	External Fixators 09/2013 - 03/2004
2	Reoperation 03/2023 - 02/2022
2	Transjugular Intrahepatic Portasystemic Shunt 04/2022 - 01/2017
2	Hemiarthroplasty 01/2022 - 01/2015
2	Kyphoplasty 10/2021 - 01/2018
2	Hip Replacement Arthroplasty (Total Hip Replacement) 01/2021 - 06/2004
2	Debridement 12/2013 - 02/2013
2	Mechanical Ventilators (Ventilator) 04/2012 - 02/2007
2	Thoracotomy 02/2008 - 04/2005